Does Air We Breathe Impact Pregnancy Outcomes?

Emerging research is shedding light on a growing public health concern: the air we breathe may significantly impact pregnancy outcomes. A recent study published in Environmental Science & Technology reveals that exposure to fine particulate matter (PM2.5) during pregnancy can disrupt vital metabolic processes in expectant mothers, increasing the risk of preterm and early-term births.

The study, which followed 330 pregnant women, found that elevated PM2.5 exposure was associated with measurable changes in blood chemistry. Specifically, scientists observed alterations in key metabolites such as cortexolone and lysoPE(20:3), molecules linked to higher risks of preterm (20%) and early-term (16.4%) deliveries. These metabolic shifts affect how the body digests proteins and generates energy, both of which are critical to supporting foetal development.

The implications are profound. Disruptions in protein and amino acid metabolism may hinder foetal growth and immune system development, potentially leading to long-term health challenges for newborns. The presence of these biomarkers could also offer a pathway for early detection and targeted interventions, allowing healthcare providers to mitigate risks before complications arise.

This research highlights how air pollution is not just an environmental issue but a deeply biological one, affecting the health of both mother and child at a molecular level. As urban populations grow and air quality concerns mount, these findings underscore the urgent need for real-time air quality monitoring and proactive health measures, especially for vulnerable groups like pregnant women.

One promising solution is the advancement of air purification technology. For instance, our DNO air purification systems are designed to reduce PM2.5 and other harmful airborne pollutants, offering cleaner indoor environments and a protective buffer for those most at risk.

Ultimately, improving air quality is not just about comfort, it’s a matter of maternal and foetal health. As science continues to uncover the invisible effects of pollution, the importance of clean air becomes even more apparent.

Reference: Environ. Sci. Technol. 2025, 59, 22, 10905–10918

Photo by Leah Newhouse: https://www.pexels.com/photo/woman-pregnant-in-black-and-white-striped-shirt-standing-near-bare-tree-952597/